Title : Diabetes-induced activation of caspase-3 in retina: effect of antioxidant therapy.

Pub. Date : 2002 Sep

PMID : 12448825






1 Functional Relationships(s)
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1 Effect of antioxidants on the activation of caspase-3 was determined by feeding a group of diabetic rats diet supplemented with a comprehensive mixture of antioxidants, including Trolox, alpha-tocopherol, N-acetyl cysteine, ascorbic acid, beta-carotene and selenium for 2-14 months, and also under in vitro conditions by incubating isolated retinal capillary cells with antioxidants with wide range of actions. 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid caspase 3 Rattus norvegicus