Title : Effect of N-acetyl-L-cysteine on peroxynitrite and superoxide anion production of lung alveolar macrophages in systemic sclerosis.

Pub. Date : 2002 Dec

PMID : 12446176






1 Functional Relationships(s)
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1 NAC preincubation (5 x 10(-5)M, 24h) significantly reduced (-21%) the ONOO(-) production in formyl Met-Leu-Phe (fMLP)-activated cells and slightly reduced it under resting conditions, whereas NAC preincubation was unable to modify the release of O(2)(-) both in basal condition and in fMLP-stimulated cells. N-Formylmethionine Leucyl-Phenylalanine formyl peptide receptor 1 Homo sapiens