Title : Pharmacokinetics of midazolam and 1'-hydroxymidazolam in Chinese with different CYP3A5 genotypes.

Pub. Date : 2002 Dec

PMID : 12433824






3 Functional Relationships(s)
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1 Pharmacokinetics of midazolam and 1"-hydroxymidazolam in Chinese with different CYP3A5 genotypes. 1-hydroxymethylmidazolam cytochrome P450 family 3 subfamily A member 5 Homo sapiens
2 The average AUC (0-8 h) of 1"-hydroxymidazolam was 3748 +/- 427 ng-min/ml in homozygous CYP3A5*3 subjects and 3920 +/- 402 ng-min/ml in heterozygous CYP3A5*1/*3 subjects. 1-hydroxymethylmidazolam cytochrome P450 family 3 subfamily A member 5 Homo sapiens
3 The average AUC (0-8 h) of 1"-hydroxymidazolam was 3748 +/- 427 ng-min/ml in homozygous CYP3A5*3 subjects and 3920 +/- 402 ng-min/ml in heterozygous CYP3A5*1/*3 subjects. 1-hydroxymethylmidazolam cytochrome P450 family 3 subfamily A member 5 Homo sapiens