Title : Prostaglandin catabolizing enzymes.

Pub. Date : 2002 Aug

PMID : 12432938






2 Functional Relationships(s)
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1 The primary catabolic pathway of prostaglandins and related eicosanoids is initiated by the oxidation of 15(S)-hydroxyl group catalyzed by NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) followed by the reduction of delta13 double bond catalyzed by NADPH/NADH dependent delta13-15-ketoprostaglandin reductase (13-PGR). Prostaglandins 15-hydroxyprostaglandin dehydrogenase Homo sapiens
2 The primary catabolic pathway of prostaglandins and related eicosanoids is initiated by the oxidation of 15(S)-hydroxyl group catalyzed by NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) followed by the reduction of delta13 double bond catalyzed by NADPH/NADH dependent delta13-15-ketoprostaglandin reductase (13-PGR). Prostaglandins 15-hydroxyprostaglandin dehydrogenase Homo sapiens