Title : Proteomics reveals protein profile changes in doxorubicin--treated MCF-7 human breast cancer cells.

Pub. Date : 2002 Jul 8

PMID : 12430184






1 Functional Relationships(s)
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1 Based on the proteome map, we found that DOX causes a markedly decrease in the levels of three isoforms of heat shock protein 27 (HSP27) whereas the levels of other stress associated proteins including HSP60, calreticulin, and protein disulfide isomerase were not significantly altered in DOX-treated MCF-7 cells. Doxorubicin calreticulin Homo sapiens