Title : Mutations in the VHL gene in sporadic apparently congenital polycythemia.

Pub. Date : 2003 Feb 15

PMID : 12393546






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The tumor suppressor von Hippel-Lindau (VHL) participates in the hypoxia-sensing pathway, as it binds to the proline-hydroxylated form of the hypoxia-inducible factor 1alpha (HIF-1alpha) and mediates its ubiquitination and proteosomal degradation. Proline von Hippel-Lindau tumor suppressor Homo sapiens