Title : Studies on intestinal absorption of sulpiride (2): transepithelial transport of sulpiride across the human intestinal cell line Caco-2.

Pub. Date : 2002 Oct

PMID : 12392092






2 Functional Relationships(s)
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1 The results obtained from these examinations indicated that the apical-to-basolateral transport of sulpiride is mediated by the peptide transporter PEPT1, organic cation transporters OCTN1 and OCTN2 on the apical membrane, and the basolateral peptide transporter on the basolateral membrane. Sulpiride solute carrier family 22 member 4 Homo sapiens
2 A decrease in the absorption of sulpiride may occur in coadministration protocols involving PEPT1-, OCTN1-, and OCTN2-transported drugs. Sulpiride solute carrier family 22 member 4 Homo sapiens