Title : Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.

Pub. Date : 2002 Nov

PMID : 12386133






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A common genetic variation results in aspartate (UGT2B15*1) or tyrosine (UGT2B15*2) at position 85 of the UGT2B15 protein. Tyrosine UDP glucuronosyltransferase family 2 member B15 Homo sapiens
2 A common genetic variation results in aspartate (UGT2B15*1) or tyrosine (UGT2B15*2) at position 85 of the UGT2B15 protein. Tyrosine UDP glucuronosyltransferase family 2 member B15 Homo sapiens