Title : Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.

Pub. Date : 2003 Feb 1

PMID : 12381268






1 Functional Relationships(s)
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1 Upon treatment of wild-type mice with ciprofibrate (0.05%, w/w, in diet for 2 weeks), the expression of Mdr2 (+3-fold), Mdr1a (+6-fold) and Mdr1b (+11-fold) mRNAs was clearly induced, while that of Oatp1 (-5-fold) was reduced. ciprofibrate ATP-binding cassette, sub-family B (MDR/TAP), member 4 Mus musculus