Pub. Date : 2002 Oct
PMID : 12379510
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The role of the efflux transporter P-glycoprotein in brain penetration of prednisolone. | Prednisolone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | In the present study, we have investigated the role of the multidrug resistance (mdr) P-glycoprotein (Pgp) at the blood-brain barrier in hampering the access of the synthetic glucocorticoid, prednisolone. | Prednisolone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | In the present study, we have investigated the role of the multidrug resistance (mdr) P-glycoprotein (Pgp) at the blood-brain barrier in hampering the access of the synthetic glucocorticoid, prednisolone. | Prednisolone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | In vitro, in stably transfected LLC-PK1 monolayers the human MDR1 P-glycoprotein was able to transport prednisolone present at a micromolar concentration. | Prednisolone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | The ability of Pgp to export the synthetic glucocorticoid, prednisolone, suggests that uptake of prednisolone in the human brain is impaired, leading to a discrepancy between central and peripheral actions. | Prednisolone | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | The ability of Pgp to export the synthetic glucocorticoid, prednisolone, suggests that uptake of prednisolone in the human brain is impaired, leading to a discrepancy between central and peripheral actions. | Prednisolone | ATP binding cassette subfamily B member 1 | Homo sapiens |