Title : Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo.

Pub. Date : 2002 Nov

PMID : 12376368






1 Functional Relationships(s)
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1 Upregulation of VEGF mRNA by hypoxia was mimicked by CoCl2 and desferrioxamine in normoxic AEC and was not prevented by inhibitors of reactive oxygen species, suggesting that hypoxic VEGF regulation involved an O2-dependent protein that requires ferrous ions but is independent of reactive oxygen species generation. Deferoxamine vascular endothelial growth factor A Rattus norvegicus