Title : [Partial synthesis and properties of des-A1-glycine-insulin (author's transl)].

Pub. Date : 1975 Jun

PMID : 1237459






2 Functional Relationships(s)
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1 A) Via complete reaction of A-chain from bovine insulin with 150 equivalents of phenylisothiocyanate in pyridine/water and trifluoroacetic acid cleavage of the resulting phenylthiocarbamoyl A-chain. Trifluoroacetic Acid insulin Bos taurus
2 B) Via reaction of bovine insulin with about 20 equivalents of phenylisothiocyanate until a substitution degree of 2.3-2.5 was reached, trifluoroacetic acid cleavage of the crude derivatives and oxidative sulphitolysis of the resulting desaminoacyl insulins. Trifluoroacetic Acid insulin Bos taurus