Title : Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering.

Pub. Date : 2002 Nov

PMID : 12371961






1 Functional Relationships(s)
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1 The effects of simvastatin on t-PA and PAI-1 expression as well as on cell shape were completely mimicked by cytochalasin D, a disrupter of cellular actin filaments, but not by colchicine, a disrupter of microtubules. Cytochalasin D plasminogen activator, tissue type Homo sapiens