Pub. Date : 2001 Dec
PMID : 12369927
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Similar to other nucleotide binding proteins, dUTPase also consists of a sequence motif rich in glycine residues known as P-loop motif. | Glycine | Deoxyuridine triphosphatase | Drosophila melanogaster |
| 2 | One of the main reasons for this limited information is the lack of the three-dimensional structure of a dUTPase enzyme with an ordered Gly-rich P-loop motif with a bound substrate and Mg(2+) ion. | Glycine | Deoxyuridine triphosphatase | Drosophila melanogaster |
| 3 | This review presents an insight into the role of Gly-rich P-loop motif in the function of dUTPase as revealed from the crystal structure. | Glycine | Deoxyuridine triphosphatase | Drosophila melanogaster |
| 4 | The analysis reveals the Gly-rich P-loop motif of dUTPase to be the longest in terms of its amino-acid composition as compared to other nucleotide binding proteins and exhibit a high-degree of sequence conservation among spectrum of species. | Glycine | Deoxyuridine triphosphatase | Drosophila melanogaster |