Title : Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes.

Pub. Date : 2002 Oct

PMID : 12369894






1 Functional Relationships(s)
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1 Similarly, the steroid family of orphan receptors, the constitutive androstane receptor (CAR) and pregnane X receptors (PXR), heterodimerize with the retinoid X receptor (RXR), transcriptionally activate the promoters of CYP2B and CYP3A gene expression by xenobiotics such as phenobarbital-like compounds (CAR) and dexamethasone and rifampin-type of agents (PXR). Phenobarbital cytochrome P450 family 3 subfamily A member 4 Homo sapiens