Title : Soluble factor-mediated differentiation of CD4+CD8+ thymocytes to single positives in vitro.

Pub. Date : 2002 Oct

PMID : 12366378






2 Functional Relationships(s)
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1 In particular, it was found that thymocyte culture with Con A sup generated CD69+DP cells, and the CD69+DP differentiated to CD8 SP under the suspension culture with soluble factors. dp CD69 molecule Homo sapiens
2 Thus, Con A sup or combinations of IL-2, IL-4 and IL-7 strongly induced differentiation of CD69+DP to CD8 SP, whereas individual cytokines did not. dp CD69 molecule Homo sapiens