Title : The Glu298Asp polymorphism of the NOS 3 gene as a determinant of the baseline production of nitric oxide.

Pub. Date : 2002 Oct

PMID : 12359981






1 Functional Relationships(s)
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1 OBJECTIVE: To investigate functional differences between the various genotypes with respect to basal nitric oxide (NO) production, we estimated the response to endothelial NO synthase (ecNOS) inhibition by infusion of increasing doses of N(G)-monomethyl-L-arginine (L-NMMA) into the brachial artery during venous occlusion plethysmography. omega-N-Methylarginine nitric oxide synthase 3 Homo sapiens