Pub. Date : 2002 Dec 6
PMID : 12359725
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2. | Threonine | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Taken together, these data show a new role for ERK in G1 cell cycle progression: In addition to its role in stimulating cyclin D1 expression and nuclear translocation of CDK2, ERK regulates Thr-160 phosphorylation of CDK2-cyclin E. | Threonine | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | Taken together, these data show a new role for ERK in G1 cell cycle progression: In addition to its role in stimulating cyclin D1 expression and nuclear translocation of CDK2, ERK regulates Thr-160 phosphorylation of CDK2-cyclin E. | Threonine | mitogen-activated protein kinase 1 | Homo sapiens |