Title : Cyclic AMP differentially modulates CD40L expression on human nai;ve and memory CD4(+) T cells.

Pub. Date : 2002 Oct 1

PMID : 12234621






3 Functional Relationships(s)
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Protein Name
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1 cAMP inhibited CD3-induced CD40L in both nai;ve and memory subsets, although greater inhibition was observed in memory cells. Sodium Iodide cathelicidin antimicrobial peptide Homo sapiens
2 In primed T cells, cAMP increased CD40L on nai;ve cells but inhibited expression on memory cells. Sodium Iodide cathelicidin antimicrobial peptide Homo sapiens
3 Differential cAMP effects appear interrelated to calcium signaling since the level of CD40L induced by calcium ionophore was increased by cAMP in both cell subsets, although nai;ve cells were more calcium responsive. Sodium Iodide cathelicidin antimicrobial peptide Homo sapiens