Pub. Date : 2000 Nov
PMID : 12214088
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | H2O2-treatment resulted in dose-dependent increases in cell death due to genomic and mitochondrial DNA damage associated with increased levels of 8-OHdG and the p53 and CD95 pro-apoptosis genes, reduced levels of the Bcl-2 survival gene, activation of JNK and p38 stress kinases, and inhibition of PI3 kinase survival signaling. | Hydrogen Peroxide | tumor protein p53 | Homo sapiens |