Title : Metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) by human cytochrome P450-dependent monooxygenase systems.

Pub. Date : 2002 Sep 11

PMID : 12207498






1 Functional Relationships(s)
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1 Although major CYPs in human liver such as CYP2C8, CYP2C9, and CYP3A4 showed no significant metabolism toward the PCDDs, CYP1A1 and CYP1A2 showed high catalytic activity toward DD and mono-, di-, and trichloroDDs. dibenzo(1,4)dioxin cytochrome P450 family 1 subfamily A member 2 Homo sapiens