Title : Leu-574 of HIF-1alpha is essential for the von Hippel-Lindau (VHL)-mediated degradation pathway.

Pub. Date : 2002 Nov 1

PMID : 12205091






2 Functional Relationships(s)
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1 In particular, the von Hippel-Lindau (VHL) protein complex, an E3 ubiquitin ligase, binds to the ODD upon hydroxylation of HIF-1alpha Pro-564. Proline von Hippel-Lindau tumor suppressor Homo sapiens
2 In particular, the von Hippel-Lindau (VHL) protein complex, an E3 ubiquitin ligase, binds to the ODD upon hydroxylation of HIF-1alpha Pro-564. Proline von Hippel-Lindau tumor suppressor Homo sapiens