Pub. Date : 2002 Sep
PMID : 12204819
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A concentration of > 0.2 nM TPA or 0.12 ng/mL (0.02 nM) EGF produced a significant increase in transformation response as well as in extracellular signal-regulated protein kinase (ERK), SRE, or AP-1 activation. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 2 | These findings suggest that the signaling pathway leading to the activation of ERK, TCF, and AP-1 proteins constitutes a major factor determining the risk of tumor promotion by TPA or EGF. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |