Pub. Date : 2002 Aug
PMID : 12201364
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cold induces catalytic iron release of cytochrome P-450 origin: a critical step in cold storage-induced renal injury. | Iron | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 2 | Whether the cytochrome P-450 enzymes, shown to be a source for iron in several injury models, contribute to cold-induced iron release is not known. | Iron | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 3 | Whether the cytochrome P-450 enzymes, shown to be a source for iron in several injury models, contribute to cold-induced iron release is not known. | Iron | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 4 | As microsomes are rich in iron-containing cytochrome P-450 enzymes, microsomes were cold stored with P-450 inhibitors, cimetidine and piperonyl butoxide. | Iron | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
| 5 | Our data demonstrate for the first time that cold-induced catalytic iron release may be at least in part of microsomal cytochrome P-450 origin, and that it participates in cold-storage-induced renal injury. | Iron | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |