Title : Quantitative comparison of the cytocidal effect of seven macrolide antibiotics on human periodontal ligament fibroblasts.

Pub. Date : 2002 Aug

PMID : 12200967






2 Functional Relationships(s)
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1 The effect of the antibiotics on the mRNA expression of alkaline phosphatase (ALP) and type I procollagen (COL) was examined in Pel cells exposed for 48 h to RXM, CAM, AZM, and EM, which exhibited strong, moderate, and weak cytocidal activity. Azithromycin alkaline phosphatase, placental Homo sapiens
2 The constitutive levels of both ALP and COL mRNA were retained in cells exposed to RXM at < or = 3 microM, CAM at < or = 10 microM, and AZM or EM at < or = 3 microM. Azithromycin alkaline phosphatase, placental Homo sapiens