Title : Postsynaptic 5-HT(1A) receptors mediate an increase in locomotor activity in the monoamine-depleted rat.

Pub. Date : 2002 Aug

PMID : 12185404






1 Functional Relationships(s)
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1 RATIONALE: In animal models of reduced dopamine transmission, such as haloperidol-induced catalepsy or monoamine-depleted animals, serotonin (5-hydroxytryptamine; 5-HT) 5-HT(1A) agonists appear to enhance motor activity. Haloperidol 5-hydroxytryptamine receptor 1A Rattus norvegicus