Title : Sympatho-inhibitory properties of various AT1 receptor antagonists.

Pub. Date : 2002 Jun

PMID : 12184061






1 Functional Relationships(s)
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1 The order of potency regarding inhibition of the Ang II-induced DBP increase was candesartan > embusartan = valsartan = eprosartan = telmisartan > irbesartan > losartan (comparison of the antagonist concentration, in the presence of which twice the agonist concentration, in the presence of which twice the agonist concentration is needed to cause the same effect [pA2 values], differences significant at P < 0.05). Valsartan angiotensinogen Rattus norvegicus