Title : Positron emission tomography: quantitative measurement of brain acetylcholinesterase activity using radiolabeled substrates.

Pub. Date : 2002 Jul

PMID : 12183113






1 Functional Relationships(s)
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1 We tested several radiolabeled lipophilic acetylcholine analogs, e.g., N-methylpiperidyl esters, which readily entered the brain via the blood-brain barrier, were hydrolyzed selectively by AChE, and were then trapped in the brain. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens