Title : Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells.

Pub. Date : 2002 Jul 15

PMID : 12172639






2 Functional Relationships(s)
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1 hEAG channels were most sensitive to imipramine (IC50: 3.4 microM at +50 mV), followed by KCa (13.8 microM at +50 mV) and Clvol (12 microM at -100 mV), indicating that hEAG expression may be of importance for proliferation of melanoma cells. Imipramine potassium voltage-gated channel subfamily H member 1 Homo sapiens
2 hEAG channels were most sensitive to imipramine (IC50: 3.4 microM at +50 mV), followed by KCa (13.8 microM at +50 mV) and Clvol (12 microM at -100 mV), indicating that hEAG expression may be of importance for proliferation of melanoma cells. Imipramine potassium voltage-gated channel subfamily H member 1 Homo sapiens