Title : Circumvention of chaperone requirement for aggregate formation of a short polyglutamine tract by the co-expression of a long polyglutamine tract.

Pub. Date : 2002 Oct 4

PMID : 12161426






1 Functional Relationships(s)
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1 In this study, we found that the co-expression of a long polyglutamine tract, which formed aggregates independently of the function of Hsp104, enhanced the formation of aggregates of a short polyglutamine tract in wild-type cells as well as in Deltahsp104 mutant cells. polyglutamine chaperone ATPase HSP104 Saccharomyces cerevisiae S288C