Title : ERK activation and nuclear translocation in amyloid-beta peptide- and iron-stressed neuronal cell cultures.

Pub. Date : 2002 Jul

PMID : 12153530






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The mitogen-activated protein/ERK kinase (MEK) inhibitor U0126 blocked ERK and caspase 3 activation, suppressed ERK translocation and reduced the number of apoptotic cells, suggesting a central role for the ERK signalling cascade in A beta(1-40) plus Fe(2+) (A beta(1-40)/Fe(2+)) -induced apoptotic death. U 0126 caspase 3 Homo sapiens