Title : P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system.

Pub. Date : 2002 Jul 5

PMID : 12151016






2 Functional Relationships(s)
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1 These are characteristic properties of the P2X(7) subtype, and we provide in situ evidence that application of the P2X(7) receptor agonist benzoyl-benzoyl ATP (BzATP) evokes raised [Ca(2+)](i) in optic nerve glia, and that the dye YO-PRO-1, which passes through pore-forming P2X(7) receptors, is taken up by astrocytes, oligodendrocytes and microglia. 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate lamin A/C Homo sapiens
2 These are characteristic properties of the P2X(7) subtype, and we provide in situ evidence that application of the P2X(7) receptor agonist benzoyl-benzoyl ATP (BzATP) evokes raised [Ca(2+)](i) in optic nerve glia, and that the dye YO-PRO-1, which passes through pore-forming P2X(7) receptors, is taken up by astrocytes, oligodendrocytes and microglia. 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate lamin A/C Homo sapiens