Title : Downregulation of COX-2 and iNOS by amentoflavone and quercetin in A549 human lung adenocarcinoma cell line.

Pub. Date : 2002 May-Jun

PMID : 12144868






3 Functional Relationships(s)
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1 Downregulation of COX-2 and iNOS by amentoflavone and quercetin in A549 human lung adenocarcinoma cell line. Quercetin nitric oxide synthase 2 Homo sapiens
2 In another set of experiment, quercetin inhibited iNOS protein expression completely without affecting iNOS mRNA expression. Quercetin nitric oxide synthase 2 Homo sapiens
3 Taken together, our data indicated that amentoflavone and quercetin differentially exerted supression of PGE(2) biosynthesis via downregulation of COX-2/iNOS expression. Quercetin nitric oxide synthase 2 Homo sapiens