Title : Galanthamine as bis-functional ligand for the acetylcholinesterase.

Pub. Date : 2002 Jun

PMID : 12140604






1 Functional Relationships(s)
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1 Acetylcholinesterase plays a key role in the development of Alzheimer"s disease as this enzyme is responsible for cleavage of the neurotransmitter acetylcholine, and, according to recent investigations, also promotes aggregation of beta-amyloid peptides, which causes plaque formation in synaptic areas. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens