Title : The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells.

Pub. Date : 2002 Aug

PMID : 12139741






2 Functional Relationships(s)
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1 Treatment with all-trans retinoic acid (ATRA) reduced Bcl-2 and Bcl-X(L) expression in the leukaemic Q cells, and enhanced their chemosensitivity to cytosine arabinoside (ara-C). Tretinoin BCL2 apoptosis regulator Homo sapiens
2 Treatment with all-trans retinoic acid (ATRA) reduced Bcl-2 and Bcl-X(L) expression in the leukaemic Q cells, and enhanced their chemosensitivity to cytosine arabinoside (ara-C). Tretinoin BCL2 apoptosis regulator Homo sapiens