Title : N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis.

Pub. Date : 2002 Jul

PMID : 12135032






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 OBJECTIVES: 5-Aminosalicylate is metabolized in colonic mucosa by N-acetyltransferase 1 (NAT1), and sulfapyridine is metabolized in the liver by N-acetyltransferase 2 (NAT2). Mesalamine N-acetyltransferase 1 Homo sapiens
2 OBJECTIVES: 5-Aminosalicylate is metabolized in colonic mucosa by N-acetyltransferase 1 (NAT1), and sulfapyridine is metabolized in the liver by N-acetyltransferase 2 (NAT2). Mesalamine N-acetyltransferase 1 Homo sapiens