Pub. Date : 2002 May-Jun
PMID : 12132693
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Alanine reverses the inhibitory effect of phenylalanine on acetylcholinesterase activity. | Alanine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | The aim of this work was to evaluate, in vitro, the effect of L-alanine (Ala) on suckling rat brain acetylcholinesterase (AChE) and on eel Electrophorus electricus pure AChE inhibited by L-phenylalanine (Phe) as well as to investigate whether Phe or Ala is a competitive inhibitor or an effector of the enzyme. | Alanine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | AChE activity was determined in brain homogenates and in the pure enzyme after 1 h preincubation with 1.2 mM of Phe or Ala as well as with Phe plus Ala. | Alanine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | Ala reversed completely the inhibited AChE by Phe (18-20% in 500-600 microM substrate, p<0.01). | Alanine | acetylcholinesterase (Cartwright blood group) | Homo sapiens |