Pub. Date : 2002 Jul 1
PMID : 12127263
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Previous work had shown that DCA produces tumors in mice that display a diffuse immunoreactivity to a c-Jun antibody (Santa Cruz Biotechnology, SC-45), whereas TCA-induced tumors do not stain with this antibody. | Dichloroacetic Acid | jun proto-oncogene | Mus musculus |
| 2 | In the present study, we compared the c-Jun phenotype of tumors induced by DCA or TCA alone to those induced when they are given together in various combinations and to those induced by TRI given in an aqueous vehicle. | Dichloroacetic Acid | jun proto-oncogene | Mus musculus |
| 3 | When given in various combinations, DCA and TCA produced a few tumors that were c-Jun+, many that were c-Jun-, but a number with a mixed phenotype that increased with the relative dose of DCA. | Dichloroacetic Acid | jun proto-oncogene | Mus musculus |
| 4 | When given in various combinations, DCA and TCA produced a few tumors that were c-Jun+, many that were c-Jun-, but a number with a mixed phenotype that increased with the relative dose of DCA. | Dichloroacetic Acid | jun proto-oncogene | Mus musculus |