Title : Novel mechanism of Vitamin E protection against cyclosporine A cytotoxicity in cultured rat hepatocytes.

Pub. Date : 2002 Jul 15

PMID : 12123747






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In cells incubated in the presence of CsA, there was an increase in the expression and activity of MnSOD and CuZnSOD but not in that of catalase and GPx. Cyclosporine superoxide dismutase 2 Rattus norvegicus
2 However, when hepatocytes were coincubated with CsA and VitE, an increase in the expression and activity in all antioxidant enzymes (MnSOD, CuZnSOD, catalase and GPx) was observed. Cyclosporine superoxide dismutase 2 Rattus norvegicus