Title : Recent landmark clinical trials: how do they modify the therapeutic paradigm?

Pub. Date : 2002 Jul

PMID : 12121010






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1 Indeed, in the recently published landmark trials of angiotensin I receptor antagonists, including the Irbesartan Diabetic Nephropathy Trial (IDNT) and Reduction of Endpoints in Non-insulin-dependent Diabetes Mellitus with the Angiotensin II Antagonist Losartan (RENAAL), multiple antihypertensive drugs were required to attain goal. renaal angiotensinogen Homo sapiens