Pub. Date : 2002 Jul 1
PMID : 12117737
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients. | Simvastatin | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 2 | METHODS AND RESULTS: In this study, we asked whether simvastatin can influence in vitro and in vivo production of the proinflammatory cytokines interleukin (IL)-6, IL-8, and monocyte chemoattractant protein-1. | Simvastatin | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 3 | Furthermore, simvastatin decreased the expression of IL-6, IL-8, and monocyte chemoattractant protein-1 mRNA in peripheral blood mononuclear cells. | Simvastatin | C-X-C motif chemokine ligand 8 | Homo sapiens |