Title : Urokinase upregulates matrix metalloproteinase-9 expression in THP-1 monocytes via gene transcription and protein synthesis.

Pub. Date : 2002 Nov 1

PMID : 12117412






1 Functional Relationships(s)
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1 Recombinant uPA induced the release of MMP9/gelatinase B, as detected by zymography and Western blotting, and this release was abolished by actinomycin D and cycloheximide (inhibitors of DNA transcription and protein synthesis) and partially suppressed by monensin (an inhibitor of secretion). Cycloheximide plasminogen activator, urokinase Homo sapiens