Title : Progesterone attenuates the inhibitory effects of cardiotonic digitalis on pregnenolone production in rat luteal cells.

Pub. Date : 2002

PMID : 12112021






1 Functional Relationships(s)
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1 Digoxin or digitoxin, but not ouabain, decreased the basal and human chorionic gonadotropin (hCG)-stimulated progesterone secretion as well as the activity of cytochrome P450 side chain cleavage enzyme (P450scc) in luteal cells. Digitoxin cytochrome P450 family 11 subfamily A member 1 Homo sapiens