Title : Different modes of action of catecholamine-O-methyltransferase inhibitors entacapone and tolcapone on adenylyl cyclase activity in vitro.

Pub. Date : 2002 May

PMID : 12111468






3 Functional Relationships(s)
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1 Different modes of action of catecholamine-O-methyltransferase inhibitors entacapone and tolcapone on adenylyl cyclase activity in vitro. Tolcapone catechol-O-methyltransferase Rattus norvegicus
2 Catechol-O-methyltransferase (COMT) inhibitors such as entacapone and tolcapone are used as adjuncts to L-DOPA ( l-3,4-dihydroxyphenylalanine, levodopa) in the treatment of Parkinson"s disease. Tolcapone catechol-O-methyltransferase Rattus norvegicus
3 Catechol-O-methyltransferase (COMT) inhibitors such as entacapone and tolcapone are used as adjuncts to L-DOPA ( l-3,4-dihydroxyphenylalanine, levodopa) in the treatment of Parkinson"s disease. Tolcapone catechol-O-methyltransferase Rattus norvegicus