Title : Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2.

Pub. Date : 2002 Sep 27

PMID : 12110689






1 Functional Relationships(s)
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1 Furthermore, a specific ERK1/2 phosphorylation inhibitor, U0126, completely blocked both FGF-2-stimulated Runx2 phosphorylation and osteocalcin promoter activity, indicating that this regulation requires the MAPK pathway. U 0126 fibroblast growth factor 2 Mus musculus