Title : RhoA inactivation inhibits cell migration but does not mediate the effects of polyamine depletion.

Pub. Date : 2002 Jul

PMID : 12105848






1 Functional Relationships(s)
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1 METHODS: Polyamines were depleted in intestinal epithelial cell (IEC)-6 cells by incubating them for 4 days with 5 mmol/L alpha-difluoromethylornithine (DFMO), which inhibits ornithine decarboxylase, the first rate-limiting enzyme in the synthesis of polyamines. Eflornithine ornithine decarboxylase 1 Rattus norvegicus