Title : Phosphatidylinositol 3-kinase and extracellular signal-regulated kinase are recruited for Fc receptor-mediated phagocytosis during monocyte-to-macrophage differentiation.

Pub. Date : 2002 Jul

PMID : 12101269






1 Functional Relationships(s)
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1 However, upon differentiation of THP-1 monocytes to macrophages, through treatment with retinoic acid and interferon-gamma (IFN-gamma), wortmannin and PD98059 blocked Fc receptor-mediated phagocytosis efficiently. Tretinoin GLI family zinc finger 2 Homo sapiens