Pub. Date : 2002 Jul
PMID : 12100562
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This peculiar H2O2 tolerance defect, the nature of the proteins of the Msn2/4 regulon, and the partial overlap of this regulon with the Yap1 H2O2-response regulon, suggest an independent and distinctive role of these two H2O2 stress response pathways. | Hydrogen Peroxide | DNA-binding transcription factor YAP1 | Saccharomyces cerevisiae S288C |
| 2 | This peculiar H2O2 tolerance defect, the nature of the proteins of the Msn2/4 regulon, and the partial overlap of this regulon with the Yap1 H2O2-response regulon, suggest an independent and distinctive role of these two H2O2 stress response pathways. | Hydrogen Peroxide | DNA-binding transcription factor YAP1 | Saccharomyces cerevisiae S288C |
| 3 | This, and the normal H2O2 induction of a gene reporter under control of the Yap1 regulator when intracellular cAMP level are high, demonstrate that the Ras-cAMP pathway negatively affects the H2O2 stress response through Msn2/4. | Hydrogen Peroxide | DNA-binding transcription factor YAP1 | Saccharomyces cerevisiae S288C |
| 4 | This, and the normal H2O2 induction of a gene reporter under control of the Yap1 regulator when intracellular cAMP level are high, demonstrate that the Ras-cAMP pathway negatively affects the H2O2 stress response through Msn2/4. | Hydrogen Peroxide | DNA-binding transcription factor YAP1 | Saccharomyces cerevisiae S288C |
| 5 | However, the high H2O2 sensitivity of a strain lacking the PKA-negative regulatory subunit Bcy1, is not only the consequence of the inhibition of Msn2/4 but also of Yap1 through a yet undefined mechanism. | Hydrogen Peroxide | DNA-binding transcription factor YAP1 | Saccharomyces cerevisiae S288C |