Title : Bivalent ligands with rigid double-stranded DNA spacers reveal structural constraints on signaling by Fc epsilon RI.

Pub. Date : 2002 Jul 15

PMID : 12097389






1 Functional Relationships(s)
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1 The results indicate that structural constraints on cross-linked IgE-Fc epsilon RI complexes imposed by these rigid DNP-dsDNA ligands prevent robust activation of signaling immediately downstream of early tyrosine phosphorylation events. dnp Fc epsilon receptor Ia Homo sapiens