Title : Lack of cell-cycle specific effects of tumor necrosis factor-alpha on tumor cells in vitro: implications for combination tumor therapy with doxorubicin.

Pub. Date : 2002

PMID : 12094545






1 Functional Relationships(s)
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1 Here, we determined the cytotoxic effect of TNF-alpha on several tumor cell lines in vitro in combination with doxorubicin (cell-cycle dependent) or melphalan (cell-cycle independent), and its effect on cell-cycle progression. Melphalan tumor necrosis factor Rattus norvegicus